Unusual Cytoplasmic Body in Lymphoid Cells of Homosexual Men with Unexplained Lymphadenopathy

Unexplained chronic generalized lymphadenopathy has recently been reported in homosexual men in several metropolitan areas in the United States.1 Lymph-node biopsies from these patients have shown reactive lymphoid hyperplasia by light microscopy. Concurrently, there have been reports of a new acquired immune-deficiency syndrome (AIDS) manifested by neoplasms and opportunistic infections; this condition has appeared in the same time period, geographic locations, and population groups as the unexplained lymphadenopathy.2 3 4 5 Lymphadenopathy may represent an early stage of AIDS, since it has preceded this syndrome in many cases.5 , 6 Early diagnosis, treatment, and prevention of AIDS have been seriously hampered by the lack of . . .