Why the study?
Guideline-adherent OAC management improves outcomes in nonvalvular atrial fibrillation, but limited data are available from Asia.
Does guideline-adherent oral anticoagulant management improve clinical outcomes in patients with nonvalvular atrial fibrillation compared to undertreatment or overtreatment?
Does guideline-adherent oral anticoagulant management improve clinical outcomes in patients with nonvalvular atrial fibrillation compared to undertreatment or overtreatment?
In a Thai cohort of patients with nonvalvular atrial fibrillation, adherence to OAC guidelines was associated with lower risks of stroke, bleeding, and death compared to undertreatment or overtreatment.
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May support guideline-adherent OAC in nonvalvular AF; leaves open causal confirmation by RCTs.
Krittayaphong et al. (2020) studied this question.
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