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May 24, 2012BMC BiologyOpen Access

MAVS ubiquitination by the E3 ligase TRIM25 and degradation by the proteasome is involved in type I interferon production after activation of the antiviral RIG-I-like receptors

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Authors

CCCéline CastanierNZNaïma ZemirliAPA Portier

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Castanier et al. (2012) studied this question.

synapsesocial.com/papers/6a8256a3fe5ce613f33acd2bhttps://doi.org/10.1186/1741-7007-10-44
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Also Consider

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  1. 1Ubiquitin-Regulated Recruitment of IκB Kinase ε to the MAVS Interferon Signaling Adapter2009 · 83 citations
  2. 2Oestrogen causes degradation of KLF5 by inducing the E3 ubiquitin ligase EFP in ER-positive breast cancer cells2011 · 47 citations
  3. 3Essential role of IPS-1 in innate immune responses against RNA viruses2006 · 502 citations