Radiation Therapy-Induced Cardiovascular Disease Treated by a Percutaneous Approach

1 51-year-old woman with severe aortic stenosis and bilateral ostial coronary artery disease (symptomatic for dyspnea, NYHA III functional class), with a history of radiotherapy at age 2 for pulmonary sarcoma and prohibitive surgical risk.

Percutaneous treatment consisting of stenting in the right coronary artery and left main ostia with drug-eluting stents, followed by transcatheter aortic valve replacement (TAVR) with transfemoral implantation of a 23 mm Edwards SAPIEN XT valve.

Procedural success, complications, and functional class (NYHA) at follow-up.