January 1, 2012Evidence-based Complementary and Alternative MedicineOpen Access

Ginseng Berry Extract Prevents Atherogenesis via Anti-Inflammatory Action by Upregulating Phase II Gene Expression

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Why the study?

Does Korean ginseng berry extract prevent atherogenesis in ApoE(-/-) mice fed a high-fat diet?

Population

ApoE(-/-) mice fed a high fat-diet and primary macrophages

Design

Preclinical

Authors

CKCK KimUniversity of Georgia DCDong Hui ChoUlsan College KLKyu‐Sun LeeEulji University

Discussion

Member takes

Implication

Should not yet change practice; hypothesis-generating for KGBE in human atherosclerosis.

Structured PICO

Does Korean ginseng berry extract prevent atherogenesis in ApoE(-/-) mice fed a high-fat diet?

Population

ApoE(-/-) mice fed a high fat-diet and primary macrophages

Intervention

Korean ginseng berry extract (KGBE)

Outcome

Atherosclerotic lesions and expression levels of phase II genes (HO-1 and GCL)surrogate

Korean ginseng berry extract demonstrates antiatherogenic effects in preclinical models by upregulating phase II enzymes and suppressing inflammatory gene expression.

Cite This Study

Kim et al. (2012) studied this question.

synapsesocial.com/papers/6a826054ee46c620893acf27 https://doi.org/10.1155/2012/490301

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Ginseng Berry Extract Prevents Atherogenesis via Anti-Inflammatory Action by Upregulating Phase II Gene Expression

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Ginseng Berry Extract Prevents Atherogenesis via Anti-Inflammatory Action by Upregulating Phase II Gene Expression

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider