Why the study?
Visceral organ blood circulation is impaired in aortic pathologies, and the study aimed to determine the effect of new-onset renal function impairment on postoperative mortality after EVAR and TEVAR.
Does newly onset renal function impairment increase postoperative mortality rates in patients undergoing EVAR and TEVAR procedures?
Does newly onset renal function impairment increase postoperative mortality rates in patients undergoing EVAR and TEVAR procedures?
Newly onset renal impairment following EVAR or TEVAR procedures is associated with a significantly increased risk of postoperative mortality.
May warrant enhanced renal monitoring post-EVAR/TEVAR; hypothesis-generating for renoprotective trials.
Background: Visceral organ blood circulation is seriously impaired in aortic pathologies especially aortic dissection involving descending thoracic and abdominal aorta. Herein, we aimed to determine the effect of the newly onset renal function impairment on postoperative mortality rates of the patients undergoing EVAR and TEVAR procedures. Methods: Patients who underwent an EVAR / TEVAR procedure in our clinic included in this retrospective study. Patients were divided into two groups according to the presence of renal function impairment. Mortality rates were calculated for the groups. Results: A total of 60 patients who underwent an EVAR/TEVAR procedure between November 2016 and May 2021 included in this study. Group 1 included a number of 48 (80%) patients without postoperative renal dysfunction. Group 2 included a total of 12 (20%) patients with postoperative renal function impairment. The initial analysis of the data revealed significant differences in the age and sex variables of the groups (P=0.038 and P=0.008 respectively). Then propensity score matching was performed to avoid bias in the groups. After propensity score matching Group 1 included 12 (50%) patients without postoperative renal impairment and Group 2 included 12 (50%) patients with postoperative renal dysfunction. There were no significant differences between the groups after propensity matching. Mortality rate was significantly different between the groups which was 1 patient (8.33%) in Group 1 vs 6 (50.00%) patients in Group 2 (P=0.020). Conclusions: Renal functions after EVAR/TEVAR procedures should be carefully monitored because renal impairment is closely related with postoperative mortality. We suggest that more studies with larger patient numbers should be conducted on the relation of renal functions and mortality after regularly performed EVAR/TEVAR procedures.
No takes yet. Share an insight, caveat, or question.
Sungur et al. (2023) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: