Why the study?
Does preoperative renal dysfunction affect mortality and postoperative renal failure in patients undergoing elective endovascular repair of abdominal aortic aneurysm?
Does preoperative renal dysfunction affect mortality and postoperative renal failure in patients undergoing elective endovascular repair of abdominal aortic aneurysm?
Preoperative renal dysfunction strongly predicts postoperative renal failure but does not accurately predict long-term survival in patients undergoing elective endovascular abdominal aortic aneurysm repair.
Preoperative renal dysfunction signals higher postoperative renal risk but poor survival prediction after elective EVAR; leaves open optimal risk stratification tools.
This study was aimed to assess the effect of preoperative renal dysfunction on mortality and postoperative renal failure in patients undergoing elective endovascular repair of abdominal aortic aneurysm. A total of 155 patients with a mean age of 74.9 years (+/-6.4) were included. In all, 31 patients (20%) had a preoperative creatinine level of >1.5 mg/dL, whereas 66 patients (42.6%) had an estimated glomerular filtration rate of <60 mL/min. Perioperative mortality was 2.6% with no significant difference between those with and without abnormal renal indices. Long-term survival at 4 years was 30% in patients with creatinine >1.5 mg/dL compared to over 60% in those with normal creatinine (P < .02). The difference in long-term survival was not as significant in patients with normal or reduced glomerular filtration rate (P = .13). However, neither creatinine nor glomerular filtration rate were found to accurately predict survival even though both demonstrated strong predictivity for postoperative renal failure in patients undergoing elective endovascular repair of abdominal aortic aneurysm.
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Soong et al. (2008) studied this question.
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