Why the study?
Does sex affect the cardiopulmonary and neuromuscular response to high-intensity interval exercise?
Does sex affect the cardiopulmonary and neuromuscular response to high-intensity interval exercise?
Physiological sex differences exist during high-intensity interval exercise, with females showing poorer initial ventilatory efficiency but greater subsequent fatigue resistance.
Sex differences in HIIT ventilatory and fatigue responses may guide individualized prescriptions; leaves open effects on clinical outcomes and training efficacy.
This study determined that males and females differ in the physiological response to high-intensity interval exercise. Specifically, females had poorer ventilatory efficiency during the first half of the task, but greater knee-extensor fatigue resistance following the task. These data build upon previous observations from constant-load exercise, demonstrating that physiological sex differences are observed during an ecologically valid exercise task commonly prescribed by practitioners in clinical and athletic populations.
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Wilson et al. (2025) studied this question.
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