SUMMARY The accumulation of deleterious mutations in a finite diploid selfing population is investigated. It is shown that the conditions for accumulation are very similar to those for the accumulation of mutations in an asexual population by ‘Muller's ratchet’. The ratchet is likely to operate in both types of population if there is a large class of slightly deleterious mutations.
No takes yet. Share an insight, caveat, or question.
Heller et al. (1978) studied this question.
Synapse has enriched one closely related paper. Consider it for comparative context: