What question did this study set out to answer?

To assess the role of vitamin D in the transition from acute to chronic pain, focusing on its potential influence on pain perception, inflammation, and nerve function.

June 1, 2025NutrientsOpen Access

Vitamin D in the Transition from Acute to Chronic Pain: A Systematic Review

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To assess the role of vitamin D in the transition from acute to chronic pain, focusing on its potential influence on pain perception, inflammation, and nerve function.
Conducted a systematic review of original research evaluating the impact of vitamin D on pain progression.
Identified and synthesized findings from 14 eligible original research articles.
Qualitative analysis revealed that vitamin D does not directly affect the progression from acute to chronic pain.
Vitamin D significantly influenced pain intensity, leading to improved clinical outcomes among patients at risk for developing chronic pain.

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Implication

Systematic review finds vitamin D modulates pain intensity rather than directly preventing chronic pain transition in high-risk patients, highlighting the need for rigorous randomized trials.

Cite This Study

Abrego-Guandique et al. (2025) studied this question.

synapsesocial.com/papers/6a8279e61ca0a24b3693bc0e https://doi.org/10.3390/nu17111912

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Implication

Systematic review finds vitamin D modulates pain intensity rather than directly preventing chronic pain transition in high-risk patients, highlighting the need for rigorous randomized trials.

Vitamin D in the Transition from Acute to Chronic Pain: A Systematic Review

Key Points

Discussion

Implication

Cite This Study

Vitamin D in the Transition from Acute to Chronic Pain: A Systematic Review

Key Points

Discussion

Implication

Cite This Study

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