Why the study?
Does a single baseline measurement of high-sensitivity CRP, LDL cholesterol, and lipoprotein(a) levels predict long-term cardiovascular disease risk in healthy female U.S. health professionals?
Does a single baseline measurement of high-sensitivity CRP, LDL cholesterol, and lipoprotein(a) levels predict long-term cardiovascular disease risk in healthy female U.S. health professionals?
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Highlights the potential of using baseline hs-CRP, LDL cholesterol, and lipoprotein(a) levels to predict long-term cardiovascular risk.
Taking a long-term view of cardiovascular disease prevention is an attractive strategy since atherosclerosis begins early in life and progresses over decades. Lowering low-density lipoprotein (LDL) cholesterol levels and improving lifestyle habits are mainstay strategies for reducing the risk of cardiovascular disease. 1 Moreover, emerging therapeutic targets include vascular inflammation as reflected by elevated levels of high-sensitivity C-reactive protein (CRP) and lipoprotein(a). Ridker et al. now report in the Journal the results of an examination of the long-term predictive value of a single baseline measurement of high-sensitivity CRP, LDL cholesterol, and lipoprotein(a) levels in nearly 28,000 healthy, female, U.S. health professionals . . .
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Blumenthal et al. (2024) studied this question.
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