Why the study?
Does carotid endarterectomy combined with aspirin and risk factor reduction prevent ipsilateral stroke in asymptomatic patients with diameter stenosis of the carotid artery of 60% or more compared to aspirin and risk factor reduction alone?
Population
Asymptomatic patients with diameter stenosis of the carotid artery of 60% or more
Comparison
Carotid endarterectomy combined with aspirin and… vs Aspirin and risk factor reduction alone
Design
Review
Follow-up
5 years
Authors
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Supports CEA for asymptomatic ≥60% stenosis if perioperative risks low; leaves open benefit versus contemporary intensive medical therapy.
Does carotid endarterectomy combined with aspirin and risk factor reduction prevent ipsilateral stroke in asymptomatic patients with diameter stenosis of the carotid artery of 60% or more compared to aspirin and risk factor reduction alone?
Carotid endarterectomy is recommended for preventing stroke in asymptomatic patients with ≥60% carotid stenosis when surgical complication rates are kept low, offering a 5.9% absolute risk reduction over 5 years.
Thomas Brott (1995) studied this question.
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