Polycarbonate and Poly(carbonate−ester)s Synthesized from Biocompatible Building Blocks of Glycerol and Lactic Acid

The synthesis and characterization of a polycarbonate of glycerol and poly(carbonate−ester)s of glycerol and l -lactic acid are reported. These new polymers possess a hydrolyzable backbone, tunable hydrophobic/hydrophilic properties, and functionalizable pendant groups. The free hydroxyl groups on the poly(glycerol- co - l -lactic acid) were derivatized with 4-isobutylmethylphenylacetic acid, a common nonsteroidal antiinflammatory drug.