Synthesis of sphingosine relatives, IX. Synthesis of (2S,3R,4E)‐1‐O‐(β‐D‐glucopyranosyl)‐N‐ [24‐(linoleoyloxy)tetracosanoyl]‐4‐sphingenine. The structure proposed for the esterified cerebroside in the epidermis of guinea pigs

Abstract (2S,3R,4E)‐1‐O‐(β‐D‐Glucopyranosyl)‐N‐[24‐(linoleoyloxy)tetracosanoyl)‐4‐sphingenine ( 1 ) was synthesized from D‐glucose ( A ), (2S,3R,4E)‐4‐sphingenine (sphingosine, B ), 24‐hydroxytetracosanoic acid ( C ) and linoleic acid ( D ). The 1 H‐NMR spectrum of synthetic 1 was different from that of the esterified cerebroside which was isolated as a tissue‐characteristic compound in the epidermis of footpad and dorsal skin of guinea pigs.