Global Burden of Early-Onset Ischemic Heart Disease, 1990 to 2019

Figures

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  Figure 1. Global ASIR of Early-Onset IHD by Sex, 2019 The age-standardized incidence rate of males (A) and females (B) early-onset ischemic heart disease in 204 countries and territories in 2019. ASIR = age-standardized incidence rate.

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  Figure 2. Trends in ASIR and ASMR of Early-Onset IHD, 1990 to 2019 Temporal trend of age-standardized incidence rate (A) and age-standardized mortality rate (B) (per 100,000 persons) for the burden of early-onset ischemic heart disease, globally and among different sociodemographic index quintiles from 1990 to 2019. SDI = sociodemographic index.

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  Figure 3. AAPC of ASR Metrics for Early-Onset IHD, 1990 to 2019 Average annual percent change of age-standardized prevalence rate (A), age-standardized incidence rate (B), and age-standardized death rate (C) for the burden of early onset ischemic heart disease, global and countries with five SDI (high, high-middle, middle, low-middle, and low) from 1990 to 2019. Black bars represent 95% confidence intervals. Abbreviation as in Figure 2.

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  Central Illustration. Global Burden of Early-Onset Ischemic Heart Disease 1990 to 2019 (Left panel) World map of the age-standardized prevalence of early-onset ischemic heart disease globally in 2019, stratified by sex. (Upper left panel) Age-standardized disability-adjusted life year rate for early-onset ischemic heart disease globally as well as for the five sociodemographic index in 2019. (Upper right panel) Average annual percentage change in the age-standardized disability-adjusted life year rate for early-onset ischemic heart disease, globally and five sociodemographic index regions. IHD = ischemic heart disease; other abbreviations as in Figures 2 and 4.

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  Figure 4. DALY Cases by Risk Factors and SDI Quintiles, 2019 The cases of disability-adjusted life year of males (A) and females (B) for early-onset ischemic heart disease attributable to 24 risk factors by global and different SDI quintiles in 2019. DALY = disability-adjusted life year; LDL = low-density lipoprotein; other abbreviation as in Figure 2.

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  Figure 5. Decomposition Analysis of Changes in the Number of Age-Standardized Disability-Adjusted Life Year, Death, Prevalence, and lncidence Rate of Early-Onset Ischemic Heart Disease by Sex, Globally, in the Sociodemographic Index Region, and the 21GBD Region, From 1990 to 2019, as a Result of Population Growth, Population Aging, and Age-Specific Rates For each component, the magnitude of a positive value indicates a corresponding increase in the corresponding indicator of early-onset ischemic heart disease attributable to that component; the magnitude of a negative value indicates a corresponding decrease in the corresponding indicator of early-onset IHD for the relevant component. Abbreviations as in Figures 2 and 4.