Asymmetric Catalytic Aminoalkylations: New Powerful Methods for the Enantioselective Synthesis of Amino Acid Derivatives, Mannich Bases, and Homoallylic Amines

Modern methodologies such as the design of chiral catalysts using combinatorial techniques play a key role in the development of asymmetric aminoalkylations. Thus, powerful enantioselective syntheses for many attractive target compounds using chiral Lewis acid or base catalysts like 1 or 2 were created.