Why the study?
Does the mechanism of the muscle metaboreflex pressor response shift from increased cardiac output to peripheral vasoconstriction when cardiac output is limited in dogs?
Population
Dogs undergoing mild dynamic exercise (3.2 km/h)
Comparison
Reduction of cardiac output via partial… vs Muscle metaboreflex activation without cardiac…
Design
Preclinical
Authors
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May inform exercise pressor responses under cardiac limitation; hypothesis-generating in animals and should not yet change practice.
Does the mechanism of the muscle metaboreflex pressor response shift from increased cardiac output to peripheral vasoconstriction when cardiac output is limited in dogs?
The muscle metaboreflex pressor response shifts from increasing cardiac output to inducing peripheral vasoconstriction when cardiac output is limited, maintaining arterial pressure.
Ichinose et al. (2009) studied this question.
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