Iron

Roland Demulder

doi:10.1001/archinte.1958.00260200082010

August 1, 1958A M A Archives of Internal Medicine

Iron

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Key Points

To outline the fundamental catalytic functions, evolutionary significance, and physiological roles of iron in biological systems and respiratory enzymes.
Narrative synthesis of biochemical evidence evaluating the presence and enzymatic activity of iron across living species, including yeast and animal organisms.
Depriving organisms of iron severely impairs development and proliferation, as shown by restricted growth in iron-free cultures of beer yeast.
Variable valency between ferrous (Fe++) and ferric (Fe+++) states enables iron to mediate electron transfer and oxidoreduction in hemoglobin, cytochromes, peroxidases, and cytochrome oxidase.

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Implication

Biological overview demonstrates the essential catalytic and respiratory roles of iron across living organisms, highlighting its fundamental requirement for cellular growth and life.

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Roland Demulder (1958) studied this question.

synapsesocial.com/papers/6a8291110bb5b6a5f21e0cbb https://doi.org/10.1001/archinte.1958.00260200082010

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Iron

Key Points

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Implication

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Iron

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Implication

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