What question did this study set out to answer?

To evaluate platelet count, spleen diameter, and their ratio as non-invasive clinical biomarkers for predicting esophageal varices in patients with cirrhosis.

January 26, 2024Gastroenterology InsightsOpen Access

Platelet Count/Spleen Diameter Ratio as a Non-Invasive Predictor of Esophageal Varices in Cirrhotic Patients: A Single-Center Experience

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Authors

SPSrinith B. PatilESIC Hospital SPSwarup Kumar PatnaikSiksha O Anusandhan University MKManjit KanungoSiksha O Anusandhan University

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Implication

Observational study reveals platelet count to spleen diameter ratio accurately predicts esophageal varices in cirrhotic patients, suggesting an effective non-invasive screening tool.

Key Points

To evaluate platelet count, spleen diameter, and their ratio as non-invasive clinical biomarkers for predicting esophageal varices in patients with cirrhosis.
Conducted a single-center observational study of consecutive cirrhotic patients without prior gastrointestinal bleeding from November 2019 to November 2021.
Evaluated patients using upper gastrointestinal endoscopy, liver function tests, abdominal ultrasonography, and complete hemograms, analyzing diagnostic performance via ROC curve analysis.
Platelet count, spleen diameter, platelet count/spleen diameter ratio, hemoglobin, and ALT levels differed significantly between patients with and without esophageal varices (p ≤ 0.05).
A platelet count/spleen diameter ratio cutoff of ≤ 1400 demonstrated a sensitivity of 90.9%, a specificity of 80.8%, and a positive predictive value of 82.56% for detecting esophageal varices.

Cite This Study

Patil et al. (2024) studied this question.

synapsesocial.com/papers/6a8292656416d6fbd1239b8a https://doi.org/10.3390/gastroent15010007

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Implication

Observational study reveals platelet count to spleen diameter ratio accurately predicts esophageal varices in cirrhotic patients, suggesting an effective non-invasive screening tool.

Platelet Count/Spleen Diameter Ratio as a Non-Invasive Predictor of Esophageal Varices in Cirrhotic Patients: A Single-Center Experience

Discussion

Member takes

Implication

Key Points

Cite This Study

Platelet Count/Spleen Diameter Ratio as a Non-Invasive Predictor of Esophageal Varices in Cirrhotic Patients: A Single-Center Experience

Discussion

Member takes

Implication

Key Points

Cite This Study

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