Validation of copper decorated Graphene oxide material for assaying Curcumin

Sensing has found its own place in the field of research. Novel and innovative ways to sense compounds have always been of great interest in the field of interdisciplinary sciences. The major problems observed with this wonder drug in stable in aqueous environment. This attributes to very minimum amount of this therapeutic in tissues and plasma. But artificial increase in curcumin concentration through supplements could have an inverse effect on the human body. As an alternative it is been commercially utilized all around the world as a dietary supplement. But, with the increased consumption of curcumin its toxicity level tends to rise in the systemic circulation. So, an alternate, fast, economical way of sensing curcumin is essential. Among all the detection systems electrochemical workstation is standing at the forefront for easy and efficient detection. we have attempted to utilize cyclic voltammetry mode for detection of our target. Three modified electrodes of Glassy Carbon electrode (GCE) were analysed -Copper, Copper-Graphene oxide (Cu-GO) modified electrode and Copper-reduced graphene oxide (Cu-rGO) modified electrode of which Cu-GO modified electrode showed better signal quality and lower detection limit than Cu-rGO modified electrode. The detection limit was found to be 4.7 nM and 0.02 nM for Cu-GO and Cu-rGO electrode respectively. The electrodes showed good reproducibility, good selectivity and a potential platform for sensing numerous compounds in future.