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A convenient and rapid method for Knoevenagel condensation has been developed by using DABCO-base ionic liquid catalysts. This method is applicable to a wide range of aromatic/aliphatic/heterocyclic/α,β-unsaturated aldehydes and ketones with active methylene compounds, and affords the corresponding substituted electrophilic alkenes in excellent yields (up to 100%) in water at room temperature within short times. The method is operationally simple and the products do not need to be purified. The use of water as the reaction medium makes the process environmentally benign. The catalysts can be recycled seven times without activity loss.
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Xu et al. (2010) studied this question.
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