The widespread occurrence of ketosis in dairy cattle has made this a disease of practical as well as of theoretical importance. Considerable work has been done in vitro on the precursors of the ketone bodies, and some work has been done i~ vivo with laboratory animals, but very little has been done with ruminants. Since ketosis is a much greater practical problem in ruminants than in any other species, and since ruminants very often do not react in the same manner as smaller laboratory animals, it was deemed desirable to study this problem using ruminants as experimental animals. A preliminary report of this work appeared earlier in abstract form (12).
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Schultz et al. (1949) studied this question.
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