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May 1, 2003Journal of Biological ChemistryOpen Access

Accumulation of Checkpoint Protein 53BP1 at DNA Breaks Involves Its Binding to Phosphorylated Histone H2AX

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Authors

IWIrene M. WardMayo Clinic in FloridaKMKay MinnNovogene Bioinformatics InstituteKJKatherine G. JordaColumbia University

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Ward et al. (2003) studied this question.

synapsesocial.com/papers/6a82a0640f52607ca18adc5dhttps://doi.org/10.1074/jbc.c300117200
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Also Consider

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  1. 1Role for the BRCA1 C-terminal Repeats (BRCT) Protein 53BP1 in Maintaining Genomic Stability2003 · 137 citations
  2. 2p53 Binding Protein 53BP1 Is Required for DNA Damage Responses and Tumor Suppression in Mice2003 · 418 citations
  3. 3DNA Double-stranded Breaks Induce Histone H2AX Phosphorylation on Serine 1391998 · 5,533 citations
  4. 4A superfamily of conserved domains in DNA damage‐ responsive cell cycle checkpoint proteins1997 · 753 citations
  5. 5Tumor Suppressor P53 Binding Protein 1 (53bp1) Is Involved in DNA Damage–Signaling Pathways2001 · 491 citations