Why the study?
Does prednisolone compared to dexamethasone improve hearing levels in patients with acute low-tone sensorineural hearing loss?
Does prednisolone compared to dexamethasone improve hearing levels in patients with acute low-tone sensorineural hearing loss?
Dexamethasone may provide better hearing outcomes than prednisolone in acute low-tone sensorineural hearing loss, potentially because the mineralocorticoid activity of prednisolone exacerbates endolymphatic hydrops.
Prednisolone was associated with worse hearing levels than dexamethasone; leaves open whether randomized trials would confirm any difference in acute low-tone hearing loss.
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Manabe et al. (2002) studied this question.
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