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His legacy to peptide science is a substantial body of work on the development of novel solid supports and orthogonal Fmoc/t-butylbased chemistry that enable solid phase peptide synthesis to be carried out under mild conditions. These were also adapted to novel automated instruments designed to operate under efficient continuous flow conditions. The chemical synthesis methods remain in widespread use today by both academia and industry.
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Atherton et al. (2019) studied this question.
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