Population
Large unilamellar vesicles composed of anionic phospholipids
Design
Preclinical
Authors
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First viroporin shown in a naked animal virus; leaves open its role in pathogenesis and therapeutic targeting.
This study provides the first evidence of viroporin activity by a protein from a naked animal virus, demonstrating that poliovirus 2B forms tetrameric aqueous pores in lipid bilayers.
Agirre et al. (2002) studied this question.
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