Why the study?
The study aimed to determine the protective role of Panax ginseng extract on lipid profiles, including total cholesterol, triglycerides, high-density lipoproteins, and low-density lipoproteins.
Does Panax ginseng aqueous extract improve lipid profiles in male rabbits treated with lead acetate?
Does Panax ginseng aqueous extract improve lipid profiles in male rabbits treated with lead acetate?
Panax ginseng aqueous extract demonstrates a protective effect on lipid profiles in a rabbit model of lead acetate toxicity.
May inform preclinical studies on ginseng for toxin-related dyslipidemia; leaves open human translation and should not change practice.
The Study involved twenty healthy adult white male rabbits (Lepus arcticus L.). the average weight (1500- 1600) Kg and aged from eight months to one year. The rabbits ware divided to four groups(G) each group contains five rabbits. G1 was treated with normal saline (1.5) ml orally as negative control group, G2 was treated with lead acetate (150) mg/kg as positive control group, G3 was treated with the aqueous extract of the Panax ginseng (400 ) mg/kg b.wt and G4 was treated with the aqueous extract of the Panax ginseng ( 400) mg/kg b.wt after 3 hours given them lead acetate (150 mg/kg b. wt/day) for peroid 30 days . study aimed to determine the protective role of Panax ginseng extract on Lipid profile like total cholesterol (TC) , triglycerides (Tg) , high-density lipoproteins (HDL) , low-density lipoproteins(LDL). The result of present study showed:- increase (P<0.05) in mean levels of high-density lipoproteins (HDL) in the (G3) and (G4) group compare with Second group (positive control G2). decrease (P<0.05) in mean levels total cholesterol (TC), triglycerides (Tg) low-density lipoproteins(LDL) in group (G3) and (G4) compare with Second group (positive control G2).
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Hamzah et al. (2022) studied this question.
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