A comparison was made between the effectiveness of sodium picosulphate and that of standardised senna in a group of 50 long-stay geriatric patients. Both were found to be equally effective as laxatives, but there were wide variations in the responses of individual patients to these agents. Side-effects were uncommon. They may well have been reduced further if a small starting dose of sodium picosulphate had been used.
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MacLennan et al. (1975) studied this question.
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