Why the study?
Do subjects with active oral herpes lesions have different HSV-1 antibody profiles compared to those without lesions?
Population
Subjects with oral herpes lesions at the time of serum sampling and subjects with no lesions
Design
Cross-sectional
Authors
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Active lesions associate with higher-efficiency HSV-1 antibodies; hypothesis-generating and should not yet change practice.
Do subjects with active oral herpes lesions have different HSV-1 antibody profiles compared to those without lesions?
Active oral herpes infection is associated with a higher proportion of neutralizing antibodies to HSV-1 virus particles.
Ratner et al. (1980) studied this question.
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