August 1, 1997Magnetic Resonance in Medicine
In vivo validation of MR pulse pressure measurement in an aortic flow model: Preliminary results
Why the study?
Does MR imaging accurately estimate vascular pulse pressure waveforms compared to a micromanometer pressure catheter in a pig aortic flow model?
Population
3 pigs weighing 25-30 kg
Comparison
MR imaging to estimate vascular pulse pressure… vs Micromanometer pressure catheter
Design
Preclinical
Authors
Discussion
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Member takes
Implication
Supports MR pulse pressure feasibility in pigs; extends phase-contrast validation but leaves open human translation.
Structured PICO
Does MR imaging accurately estimate vascular pulse pressure waveforms compared to a micromanometer pressure catheter in a pig aortic flow model?
P
Population
3 pigs weighing 25-30 kg
I
Intervention
MR imaging (phase-contrast velocity imaging) to estimate vascular pulse pressure waveforms from blood flow rates and vessel cross-sectional area
C
Comparator
Micromanometer pressure catheter
O
Outcome
Accuracy of MR-derived estimates of pressure compared to micromanometer pressure cathetersurrogate
MR-based measurement of pulse pressure and related elastic parameters is feasible using phase-contrast velocity imaging.
Limitations
- Optimization of the method will require the application of rapid imaging techniques
- Requires development of strategies for obtaining a more localized measurement
Cite This Study
Urchuk et al. (1997) studied this question.