Population
Dogs with long continued severe anemia due to bleeding
Comparison
Favorable diet periods vs Standard diets / control periods
Design
Preclinical
Follow-up
up to many years
Authors
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Variable marrow expansion in anemic dogs cautions against uniform clinical assumptions; leaves open mechanisms and human translational relevance.
In dogs with severe anemia from bleeding, red marrow spread is highly variable and hemoglobin precursors are stored during favorable diet periods rather than as mature red cells.
Oehlbeck et al. (1932) studied this question.
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