February 1, 1998AJP Heart and Circulatory Physiology

Mechanism of lidocaine block of late current in long Q-T mutant Na+ channels

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Authors

RDRobert DumaineUniversité de Sherbrooke GKGlenn E. KirschElectrophysiology

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Implication

Clarifies distinct gating defects causing late Na currents across LQT3 mutations; extends mechanistic insight while leaving clinical translation open.

Key Points

Key points are not available for this paper at this time.

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Dumaine et al. (1998) studied this question.

synapsesocial.com/papers/6a82b28fc40fc255ce133d26 https://doi.org/10.1152/ajpheart.1998.274.2.h477

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Implication

Clarifies distinct gating defects causing late Na currents across LQT3 mutations; extends mechanistic insight while leaving clinical translation open.

Mechanism of lidocaine block of late current in long Q-T mutant Na+ channels

Discussion

Member takes

Implication

Key Points

Cite This Study

Mechanism of lidocaine block of late current in long Q-T mutant Na+ channels

Discussion

Member takes

Implication

Key Points

Cite This Study

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