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TO date, relatively little work has been done on the humoral antibody response in splenectomized persons. Rowley,1 using a single intravenous injection of 2 per cent sheep red blood cells, reported that 13 of 14 splenectomized patients failed to respond with a significant antibody titer nine to fourteen days after injection whereas all of 14 controls showed a significant rise. McFadzean and Tsang2 also used the intravenous injection of sheep red blood cells, and noted that the antibody response in 10 splenectomized patients was inferior to that observed in 11 controls. However, the same workers3 found that 15 splenectomized patients . . .
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Saslaw et al. (1959) studied this question.
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