Population
190 patients with chronic kidney disease, including 38 patients with diabetic nephropathy, and 36 healthy…
Design
Cross-sectional
Authors
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Does not support changing CKD practice; leaves open urinary ACE2 as a hypothesis-generating biomarker pending validation.
Urinary ACE2 is significantly elevated in patients with CKD, particularly those with diabetic nephropathy, suggesting its potential as a non-invasive biomarker for renal ACE2 activity.
Mizuiri et al. (2011) studied this question.
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