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October 1, 2006Annals of Noninvasive ElectrocardiologyOpen Access

Patients with uncomplicated metabolic syndrome had significantly higher values of QTc-min, QTc-max, and QTd than the control group (P < 0.001).

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Why the study?

Does uncomplicated metabolic syndrome increase QTc interval and QTc dispersion compared to healthy volunteers?

Population

83 subjects, including 50 individuals with uncomplicated metabolic syndrome diagnosed according to Adult…

Comparison

Uncomplicated metabolic syndrome vs Healthy normal volunteers

Design

Case-control

Authors

SSSerdar SoydinçVDVedat DavutoğluMAMurat Akçay

Discussion

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Overview

May signal repolarization risk in metabolic syndrome; leaves open whether QT metrics predict events or warrant screening.

Structured PICO

Does uncomplicated metabolic syndrome increase QTc interval and QTc dispersion compared to healthy volunteers?

P
Population
83 subjects, including 50 individuals with uncomplicated metabolic syndrome diagnosed according to Adult Treatment Panel III criteria (11 men, 39 women) and 33 healthy normal volunteers (9 men, 24 women), matched for age and sex.
I
Intervention
Uncomplicated metabolic syndrome
C
Comparator
Healthy normal volunteers
O
Outcome
Corrected QT interval (QTc-min, QTc-max) and corrected QT dispersion (QTd) on electrocardiogramsurrogate

Uncomplicated metabolic syndrome is associated with prolonged QTc interval and increased QTc dispersion, indicating potential repolarization abnormalities that may contribute to increased cardiovascular risk.

Cite This Study

Soydinç et al. (2006) studied this question.

synapsesocial.com/papers/6a82be5544ed55722c75b62ahttps://doi.org/10.1111/j.1542-474x.2006.00123.x
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