Why the study?
Does FLI-1 immunohistochemistry distinguish Ewing sarcoma from small cell osteosarcoma and mesenchymal chondrosarcoma?
Population
Tumor samples including 10 small cell osteosarcomas, 10 mesenchymal chondrosarcomas, 8 Ewing sarcomas, and…
Design
Cross-sectional
Authors
Loading...
Negative FLI-1 supports alternative diagnoses in small round cell tumors; leaves open prospective validation before routine use.
Does FLI-1 immunohistochemistry distinguish Ewing sarcoma from small cell osteosarcoma and mesenchymal chondrosarcoma?
FLI-1 immunohistochemistry is a useful diagnostic marker to distinguish Ewing sarcoma from small cell osteosarcoma and mesenchymal chondrosarcoma, as the latter two lack FLI-1 immunoreactivity.
Lee et al. (2010) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: