A Cobalt-Catalyzed Entry Into the Ergot Alkaloids: Total Syntheses of (±)-Lysergene and (±)-LSD

All articles of this category Cocyclization of 4 -ethynyl-3-indoleacetonitriles with alkynes in the presence of CpCo(CO) 2 gives rise to the ergoline derivatives 6-9 , two of which were transformed into racemic lysergene and LSD, respectively.