Population
In vitro models and one normal male (n=1)
Design
Preclinical
Authors
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Rapid apoprotein exchange precludes HDL subfractions as stable metabolic probes in humans; leaves open alternative tracer strategies for clinical research.
Apoproteins A-I, A-II, and C exchange rapidly between HDL2 and HDL3, precluding their use as stable probes to measure HDL subfraction metabolism in humans.
Shepherd et al. (1978) studied this question.
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