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A double-blind study was undertaken to evaluate the efficacy of clindamycin hydrochloride hydrate as compared with tetracycline hydrochloride and placebo in the treatment ofMycoplasma pneumoniae. Thirty-two young adult men were studied. Clindamycin failed to cause defervescence or roentgenographic resolution more promptly than placebo. Tetracycline was associated with a shortening of the duration of fever. (JAMA228:729-731, 1974)
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Jerry D. Smilack (1974) studied this question.
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