Population
In vitro perfused hydronephrotic kidneys
Comparison
100 nM human ANP-, nitroprusside… vs Baseline pressure-induced vasoconstriction…
Design
Preclinical
Authors
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ANP does not blunt pressure-induced afferent arteriolar vasoconstriction in this model; leaves open stimulus-specific renal microvascular effects in vivo.
ANP fails to affect pressure-induced afferent arteriolar vasoconstriction, indicating that the type of underlying vasoconstrictor stimuli determines the renal microvascular response to ANP.
Hayashi et al. (1990) studied this question.
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