What question did this study set out to answer?

To describe the clinical manifestations, radiographic patterns, diagnostic testing, and therapeutic outcomes of nosocomial pulmonary disease caused by Mycobacterium xenopi linked to a hospital water system.

January 1, 1981

Clinical and roentgenographic features of nosocomial pulmonary disease due to Mycobacterium xenopi.

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Authors

ACA M Costrini DMDonald A. MahlerDartmouth College WGW. GrossUnited States Department of Veterans Affairs

Discussion

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Implication

Case series reveals nodular and cavitary presentations of waterborne Mycobacterium xenopi in hospitalized patients, indicating vulnerability among individuals with prior lung disease.

Key Points

To describe the clinical manifestations, radiographic patterns, diagnostic testing, and therapeutic outcomes of nosocomial pulmonary disease caused by Mycobacterium xenopi linked to a hospital water system.
Retrospective case series evaluating 19 patients diagnosed with nosocomial pulmonary Mycobacterium xenopi infection linked to hospital water exposure.
Assessed clinical symptoms, chest roentgenograms, comparative skin testing with M. xenopi sensitin versus PPD-tuberculin (n=12), and in vitro antimycobacterial drug susceptibility.
Documented treatment responses to standard regimens of antituberculosis medications.
Twelve of 19 patients presented with respiratory symptoms, including three with hemoptysis, while chest roentgenograms predominantly displayed nodular or mass-like shadows, cavitary lesions, or multiple nodular densities.
Skin testing in 12 individuals produced consistently larger induration diameters with M. xenopi sensitin compared to standard PPD-tuberculin.
All initial bacterial isolates were susceptible in vitro to streptomycin (2.0 µg), isoniazid (1.0 µg), and para-aminosalicylic acid (10.0 µg), resulting in successful clinical resolution with standard antituberculosis chemotherapy.

Cite This Study

Costrini et al. (1981) studied this question.

synapsesocial.com/papers/6a82cbb6aa66c98ddba0d206 https://doi.org/10.1164/arrd.1981.123.1.104

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Implication

Case series reveals nodular and cavitary presentations of waterborne Mycobacterium xenopi in hospitalized patients, indicating vulnerability among individuals with prior lung disease.

Clinical and roentgenographic features of nosocomial pulmonary disease due to Mycobacterium xenopi.

Discussion

Member takes

Implication

Key Points

Cite This Study

Clinical and roentgenographic features of nosocomial pulmonary disease due to Mycobacterium xenopi.

Discussion

Member takes

Implication

Key Points

Cite This Study

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