Key result
Female sex and smoking were independently associated with increased vascular smooth muscle cell stiffening, including apparent cell stiffness and elastic modulus.
Authors
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Female sex and smoking may influence VSMC mechanics; leaves open causal roles and clinical relevance pending prospective validation.
Cross-Sectional (n=80)
No
Effect estimate: R2 0.164
p-value: p=0.022 (female sex), p=0.018 (smoking)
Dinardo et al. (2015) conducted a cross-sectional in Chronic coronary heart disease (n=80). Female sex and smoking vs. Male sex and non-smoking was evaluated on Vascular smooth muscle cell apparent stiffness (Gr) (R2 0.164, p=p=0.022 (female sex), p=0.018 (smoking)). Female sex and smoking were independently associated with increased vascular smooth muscle cell stiffening, including apparent cell stiffness and elastic modulus.
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