November 1, 1997Anaesthesia

Thoracic epidural anaesthesia for coronary artery bypass graft surgeryEffects on postoperative complications

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Why the study?

Does thoracic epidural anaesthesia reduce postoperative complications in patients undergoing routine coronary artery bypass graft surgery?

Population

218 consecutive patients who underwent routine coronary artery bypass graft surgery

Comparison

Thoracic epidural anaesthesia with bupivacaine… vs Target-controlled infusion of alfentanil for…

Design

Cohort

Follow-up

peri-operative

Authors

DTDeborah TurfreyUniversity Hospitals Birmingham NHS Foundation Trust DRDominic A. A. RayUniversity of Virginia NSN. P. SutcliffeAlfred Health

Discussion

Member takes

Implication

Associated with fewer treated arrhythmias after CABG; hypothesis-generating and requires randomized confirmation before practice change.

Structured PICO

Does thoracic epidural anaesthesia reduce postoperative complications in patients undergoing routine coronary artery bypass graft surgery?

Population

218 consecutive patients who underwent routine coronary artery bypass graft surgery

Intervention

Thoracic epidural anaesthesia with bupivacaine and clonidine, started before surgery and continued for 5 days after surgery, added to standardised general anaesthetic (target-controlled infusions of alfentanil and propofol)

Comparator

Target-controlled infusion of alfentanil for analgesia for the first 24 h after surgery, followed by intravenous patient-controlled morphine analgesia for a further 48 h, added to standardised general anaesthetic

Outcome

Frequency of respiratory, neurological, renal, gastrointestinal, haematological and cardiovascular complicationssafety

Thoracic epidural anaesthesia during CABG is associated with a significant reduction in new arrhythmias requiring treatment and faster time to tracheal extubation compared to standard general anaesthesia.

Cite This Study

Turfrey et al. (1997) studied this question.

synapsesocial.com/papers/6a82daee8aa2f088808d693a https://doi.org/10.1111/j.1365-2044.1997.260-az0397.x

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Thoracic epidural anaesthesia for coronary artery bypass graft surgeryEffects on postoperative complications

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Thoracic epidural anaesthesia for coronary artery bypass graft surgeryEffects on postoperative complications

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider