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January 1, 1988Genetic Epidemiology

Lifestyle factors in monozygotic and dizygotic twins

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Population

106 monozygotic (MZ) and 94 like-sex dizygotic (DZ) twin pairs

Design

Cross-sectional

Authors

RHRichard F HellerGeneral / Preventive / LipidsDODianne L. O’ConnellThe University of SydneyDRD. C. K. RobertsAustralian National University

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Implication

Greater MZ lifestyle concordance may confound twin-based IHD and lipid heritability estimates; leaves open accurate genetic-environmental partitioning.

Structured PICO

P
Population
106 monozygotic (MZ) and 94 like-sex dizygotic (DZ) twin pairs
O
Outcome
Distribution and within-pair similarities of demographic and lifestyle factors (including diet, smoking, exercise, and alcohol consumption)

Monozygotic twins share lifestyle factors to a greater degree than dizygotic twins, which may confound genetic heritability estimates for IHD risk and lipid levels.

Cite This Study

Heller et al. (1988) studied this question.

synapsesocial.com/papers/6a82dec888f77a62c2a0d2efhttps://doi.org/10.1002/gepi.1370050503
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1A Proposed Test of the Difference Between the Means of Monozygotic And Dizygotic Twins1977 · 79 citations
  2. 2Heritability: One Word, Three Concepts1983 · 195 citations
  3. 3Twin study of genetic and environmental effects on lipid levels1988 · 52 citations