What is the clinical evidence from this study?

Study design: Cohort. Population: Postoperative atrial fibrillation after coronary artery bypass graft (n=999). Intervention: Demographic and clinical risk factors (e.g., age ≥65 years, EF <45%) vs. Patients without these risk factors. Primary outcome: Postoperative atrial fibrillation (POAF) (OR 3.022, p=< .001).

October 31, 2018Clinical Nursing Research

Predictors Affecting Postoperative Atrial Fibrillation in Patients After Coronary Artery Bypass Graft

Q: What are the key findings of this study?

Old age ≥65 years (OR 3.022, p<0.001) and ejection fraction <45% (OR 1.489, p=0.036) were significant predictors of postoperative atrial fibrillation after coronary artery bypass graft.

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Key result

Old age ≥65 years (OR 3.022, p<0.001) and ejection fraction <45% (OR 1.489, p=0.036) were significant predictors of postoperative atrial fibrillation after coronary artery bypass graft.

Study Design

Type

Cohort (n=999)

Structured PICO

Population

999 patients followed-up for at least 1 year after coronary artery bypass graft in South Korea to identify predictors of postoperative atrial fibrillation.

Outcome

Postoperative atrial fibrillation (POAF)

Main Result

Odds Ratio: 3.022

p-value: p=< .001

Old age, reduced ejection fraction, postoperative potassium levels, and early postoperative pain are significant predictors of postoperative atrial fibrillation following CABG.

Implication

Supports risk stratification for post-CABG POAF; leaves open whether targeted prophylaxis improves outcomes in these subgroups.

Abstract

The aim of this study is to investigate the differences in POAF (postoperative atrial fibrillation) and non-POAF patients using demographic and clinical characteristics and identify predictors affecting POAF after coronary artery bypass grafts in South Korea. This retrospective cohort study included 999 patients followed-up for at least 1 year after coronary artery bypass graft, between January 2011 and December 2015. Multivariate logistic regression was performed to assess risk factors based on demographics, as well as preoperative and postoperative characteristics. The adjusted multivariate analysis demonstrated that risk factors for POAF were old age (⩾65 years; odds ratio [OR] = 3.022, p < .001), ejection fraction less than 45% (OR = 1.489, p = .036), electrolyte potassium level after surgery (OR = 1.765, p = .003), and the average pain score on Postoperative Day 1 (OR = 1.253, p < .001). The incidence of atrial fibrillation after coronary artery bypass graft surgery can be reduced through the screening of preoperative risk factors, strict potassium monitoring, and pain management strategies.

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Cite This Study

Lee et al. (2018) conducted a cohort in Postoperative atrial fibrillation after coronary artery bypass graft (n=999). Demographic and clinical risk factors (e.g., age ≥65 years, EF <45%) vs. Patients without these risk factors was evaluated on Postoperative atrial fibrillation (POAF) (OR 3.022, p=< .001). Old age ≥65 years (OR 3.022, p<0.001) and ejection fraction <45% (OR 1.489, p=0.036) were significant predictors of postoperative atrial fibrillation after coronary artery bypass graft.

synapsesocial.com/papers/6a82e200c40fc255ce134803 https://doi.org/10.1177/1054773818809285