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Chondrosarcoma is rare, accounting for 0.2% of all malignant head and neck tumors. We report a case of chondrosarcoma arising from the nasal septum. A 63-year-old woman seen for 15-month of nasal obstruction and headache was found in rhinoscope, to have a bilaterally bulging posterior nasal septum. Computed tomography (CT) confirmed a tumorous mass extending to the sphenoid sinus and partially to the right posterior ethmoid sinus. T1- and T2-weighted magnetic resonance imaging (MRI) showed low and high intensity in spotty gadolinium enhancement. Transnasal endoscopic biopsy under general anesthesia yielded a histopathological diagnosis of chondrosarcoma. The woman refused proposed wide tumor resection for religious reasons but alternatively underwent carbon ion radiotherapy of 70.4 Gy, markedly reducing the tumor without severe complications. She has been remaining fairly well without recurrence in the 13 months since irradiation.
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Ohkubo et al. (2010) studied this question.
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