Key result
Microbial infections, including bacterial, viral, and fungal pathogens, interact with the lung allograft to alter chemokine production, increasing the risk of chronic lung allograft dysfunction and mortality.
This review highlights the mechanistic role of bacterial, viral, and fungal infections in promoting chronic lung allograft dysfunction via altered chemokine production and alloresponse.
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surveillance; leaves open targeted blockade).
Belperio et al. (2017) conducted a review in Chronic Lung Allograft Dysfunction. Microbial infections (bacterial, viral, and fungal) was evaluated. Microbial infections, including bacterial, viral, and fungal pathogens, interact with the lung allograft to alter chemokine production, increasing the risk of chronic lung allograft dysfunction and mortality.
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