Key result
Routine aspirin thromboprophylaxis after primary total hip arthroplasty reduced deaths from cardiovascular causes to 0%, compared to 0.75% without chemical thromboprophylaxis.
Why the study?
Does aspirin as chemical thromboprophylaxis reduce mortality in patients undergoing elective total hip replacement compared to no chemical thromboprophylaxis?
Population
Patients undergoing elective total hip replacement
Comparison
Aspirin as chemical thromboprophylaxis vs Historical cohort from the same unit without…
Design
Cohort
Follow-up
90 days
Authors
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Aspirin thromboprophylaxis was associated with fewer cardiovascular deaths after hip arthroplasty; hypothesis-generating and requires randomized confirmation before challenging LMWH guidelines.
Cohort
No
Does aspirin as chemical thromboprophylaxis reduce mortality in patients undergoing elective total hip replacement compared to no chemical thromboprophylaxis?
Absolute Event Rate: 0% vs 0.75%
Routine aspirin thromboprophylaxis after elective total hip replacement is associated with zero 90-day mortality and a reduction in cardiovascular deaths, challenging guidelines that recommend low molecular weight heparin for all patients.
Parry et al. (2008) conducted a cohort in Elective total hip replacement. Aspirin vs. No chemical thromboprophylaxis was evaluated on Deaths from cardiovascular causes. Routine aspirin thromboprophylaxis after primary total hip arthroplasty reduced deaths from cardiovascular causes to 0%, compared to 0.75% without chemical thromboprophylaxis.
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