Key result
This document is a journal masthead and does not contain clinical study data.
Why the study?
Individualized anticoagulation based on patient risk stratification improves outcomes after arthroplasty, and this study aimed to assess the safety and efficacy of thromboprophylaxis prescribed using a standardized Caprini Risk Score protocol.
Does individualized thromboprophylaxis based on the Caprini Risk Score prevent postoperative venous thrombosis in arthroplasty patients?
Does individualized thromboprophylaxis based on the Caprini Risk Score prevent postoperative venous thrombosis in arthroplasty patients?
A standardized risk assessment protocol using the Caprini Risk Score to guide thromboprophylaxis (aspirin for low risk, apixaban for high risk) resulted in a low VTE rate of 0.2% in arthroplasty patients.
May support Caprini-guided thromboprophylaxis with low VTE rates in arthroplasty; leaves open need for randomized confirmation.
Venous thromboembolism (VTE) is a serious and predictable complication following arthroplasty. It has been recognized that a strategy utilizing individualized anticoagulation choices based on patient risk stratification results in improved patient outcomes. A 2013 version of the Caprini Risk Score has previously been validated for use in total joint arthroplasty. A Caprini score of 10 or greater assesses the patient as “high risk” while 9 or less is considered “low risk.” Patients scored as “low risk” for postoperative VTE receive enteric coated aspirin 81 mg twice a day for 6 weeks. Patients scored as “high risk” for VTE are prescribed apixaban. This retrospective cohort study was conducted to assess the safety and efficacy of the thromboprophylaxis treatment prescribed based on a standardized risk assessment protocol for the calendar year 2020. Patients having total hip arthroplasty, total knee arthroplasty, revision total hip arthroplasty, revision total knee arthroplasty, or bilateral arthroplasties by 13 surgeons (N = 873) were reviewed. Patients were risk assessed using the Caprini Risk Score and thromboprophylaxis was prescribed based on the score obtained. The annual rate of VTE was 0.2%. The Caprini Risk Score is an effective approach to individualize thromboprophylaxis choices after total joint arthroplasty.
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Krauss et al. (2022) studied this question. This document is a journal masthead and does not contain clinical study data.
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