What question did this study set out to answer?

To elucidate the physiological mechanisms underlying exertional dyspnea and respiratory center regulation in patients with congestive heart failure.

November 1, 1932Archives of Internal Medicine

Congestive Heart Failure

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Authors

THTinsley R. HarrisonAtrium Health Wake Forest Baptist

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Implication

Physiological review uncovers mechanisms of exertion-induced dyspnea and respiratory center regulation in congestive heart failure, suggesting blood acidity shifts drive symptoms.

Key Points

To elucidate the physiological mechanisms underlying exertional dyspnea and respiratory center regulation in patients with congestive heart failure.
Reviewed historical clinical frameworks establishing effort tolerance and dyspnea as prognostic benchmarks in cardiac disease.
Synthesized physiological literature regarding arterial hydrogen ion concentration, blood acidity shifts, and respiratory center stimulation during muscular effort.
Exertional dyspnea serves as the principal clinical symptom reflecting functional cardiac impairment, prognosis, and therapeutic efficacy.
Ventilatory acceleration during physical exertion links directly to shifts toward acidity in circulating arterial blood and the respiratory center.

Cite This Study

Tinsley R. Harrison (1932) studied this question.

synapsesocial.com/papers/6a82f9e5a353bb944193c1bd https://doi.org/10.1001/archinte.1932.00150180043004

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Implication

Physiological review uncovers mechanisms of exertion-induced dyspnea and respiratory center regulation in congestive heart failure, suggesting blood acidity shifts drive symptoms.

Congestive Heart Failure

Discussion

Member takes

Implication

Key Points

Cite This Study

Congestive Heart Failure

Discussion

Member takes

Implication

Key Points

Cite This Study

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